Knowledge Library

Evidence sources

Every source in the registry, by tier. Tiers 1 and 2 can support a finding on their own; the open web only ever supplements.

Tier 1 — Government, regulators, official guidelines, coding authorities, product labels (30)

• Orphanet / Orphadata

  Epidemiology · Live API · api.orphadata.com
• NCI SEER

  Epidemiology · Live API · seer.cancer.gov
• National Cancer Institute (NCI)

  Guidelines · Live API · cancer.gov
• CDC WONDER (NVSS mortality)

  Epidemiology · Live API · wonder.cdc.gov
• WHO Global Health Observatory

  Epidemiology · Live API · ghoapi.azureedge.net
• FDA Drug Labeling (openFDA)

  Labels & regulators · Live API · api.fda.gov
• FDA Drugs@FDA (openFDA)

  Labels & regulators · Live API · api.fda.gov
• FDA NDC Directory (openFDA)

  Labels & regulators · Live API · api.fda.gov
• DailyMed

  Labels & regulators · Live API · dailymed.nlm.nih.gov
• FDA Purple Book

  Labels & regulators · Downloaded reference file · purplebooksearch.fda.gov
• NLM Clinical Tables (ICD-10-CM)

  Coding · Live API · clinicaltables.nlm.nih.gov
• NLM Clinical Tables (ICD-9-CM)

  Coding · Live API · clinicaltables.nlm.nih.gov
• NLM Clinical Tables (HCPCS)

  Coding · Live API · clinicaltables.nlm.nih.gov
• NLM Clinical Tables (LOINC)

  Coding · Live API · clinicaltables.nlm.nih.gov
• CMS ICD-10-CM Release Files

  Coding · Downloaded reference file · cms.gov
• CMS HCPCS Release Files

  Coding · Downloaded reference file · cms.gov
• CMS ICD-10-PCS Code File

  Coding · Downloaded reference file · cms.gov
• CMS ASP NDC-HCPCS Crosswalk

  Coding · Downloaded reference file · cms.gov
• CMS ICD-9-CM to ICD-10-CM GEMs

  Coding · Downloaded reference file · cms.gov
• WHO ICD-11

  Coding · Live API · id.who.int
• LOINC (Regenstrief)

  Coding · Live API · loinc.org
• AMA CPT

  Coding · Licensed: cited, never fetched · ama-assn.org
• NCCN

  Guidelines · Licensed: cited, never fetched · nccn.org
• ESMO

  Guidelines · Live API · esmo.org
• EHA (European Hematology Association)

  Guidelines · Live API · ehaweb.org
• iwCLL Guidelines (Blood)

  Guidelines · Live API · ashpublications.org
• WHO

  Guidelines · Search within the site · who.int
• CDC / NCHS

  Epidemiology · Search within the site · cdc.gov
• CMS

  Labels & regulators · Search within the site · cms.gov
• FDA

  Labels & regulators · Search within the site · fda.gov

Tier 2 — Peer-reviewed literature, trial registries, professional and disease organisations (11)

• PubMed

  Literature · Live API · pubmed.ncbi.nlm.nih.gov
• Europe PMC

  Literature · Live API · ebi.ac.uk
• Crossref

  Literature · Live API · api.crossref.org
• FDA FAERS Adverse Events (openFDA)

  Trials & registries · Live API · api.fda.gov
• ClinicalTrials.gov

  Trials & registries · Live API · clinicaltrials.gov
• NLM Clinical Tables (RxTerms)

  Labels & regulators · Live API · clinicaltables.nlm.nih.gov
• ASH / Blood (American Society of Hematology)

  Guidelines · Live API · ashpublications.org
• ASCO

  Guidelines · Live API · asco.org
• American Cancer Society

  Epidemiology · Search within the site · cancer.org
• Leukemia & Lymphoma Society

  Disease organisations · Search within the site · lls.org
• CIBMTR

  Trials & registries · Search within the site · cibmtr.org

Tier 3 — Open-web search (supplementary, lowest) (1)

• Open Web (Supplementary)

  Open web · Open-web search

Research questions

The question set each indication starts from, by research stage. Celestra scopes each question to the project before it searches.

Signed-off documents

Research documents approved in your projects, with their brief and rules where they exist.